Pipettes Buyers Guide | Sartorius

14 Jul.,2025

 

Pipettes Buyers Guide | Sartorius

Author: Dr. Emilia Varhimo | Read Time: 10 minutes | Last Updated: October

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So, you want to explore pipettes? From Techniques to Trade-Ins: The Guide to Choosing the Right Pipette for Your Application

Laboratory work is pertinent to an exceptionally broad scope of principles and professions. But for all the different research fields, there is a unifying factor – most rely on pipettes to safely and accurately transfer liquid samples and conduct repeatable experiments. Most – if not all – basic laboratory guides feature sections about pipettes and pipetting techniques. Indeed, pipetting is one of the most common tasks performed in lab settings and one of the most important. It is important to remember that pipetting is not a one-size-fits-all process. Everything from liquids to workflow can directly influence the pipettes, accessories and pipetting techniques that should be used. Because pipetting occurs so frequently in lab settings, it stands to reason a user would want to ensure proper equipment and techniques are always used.  

But what constitutes proper equipment and technique?  

There are several factors to consider regarding pipettes and pipetting but making these choices does not have to be a daunting task. Sartorius offers an all-inclusive buyers guide for selecting pipettes and pipetting accessories and a robust library of resources, so there is never a missed step when it comes to technique, maintenance, etc.  

Decisions, Decisions: Choosing the Perfect Pipette

Deciding your laboratory requires pipettes is the easy part. The breakdown of needs and variables will ultimately determine which pipette and accessory choices will make the most sense.

Quick Tip: A good rule of thumb is to remember the highest accuracy levels are achieved by choosing the smallest volume pipettes capable of handling your volumes. Pipettes are most accurate at nominal volume.

Before you purchase your next pipette, consider the following:
 

  1. For which applications will the pipettes commonly be used?
  2. What type of work is involved (Quality Control, pharmaceutical safety, life sciences)?
  3. What is the typical workflow?
  4. What are the sample materials?


Electronic Pipettes 

When the name of the game is precision – and you want to leave the variables of manual pipetting behind with the simple push of a button – it might be time to explore electronic pipettes. Sartorius Picus® 2 family pipettes are ideal for your daily liquid-handling lab requirements.

With fully electronic control, you can be sure of consistent, user-independent results. And with multiple settings, you can expedite your workflow, handling larger tasks faster than with mechanical pipettes. 

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Exploring Pipetting Needs Through Applications

Understanding the specific needs of your application can help you select the right pipette and improve your results. There is a strong correlation between lab applications and the type of pipetting equipment to get the job done in the best possible way. Everything from sample medium to sterility requirements plays a role in the types of pipettes and accessories used. Knowing which pipettes and accessories most effectively mesh with various applications can keep pipetting tasks safe, accurate and repeatable - regardless of your field. 
 

Four common applications that involve pipetting include:

  1. Cell-based Assays - Cells are typically sensitive and require careful handling in laboratory settings. To ensure optimal success in cell-based experiments, it is recommended that electronic pipettes be used with filter tips, using good pipetting techniques that eliminate foaming and bubble formation during cell seeding. 
  2. Cell Culture Work - A common hazard in cell culture work is contamination. The invasion of mold, bacteria and mycoplasma (to name a few) is detrimental to the sample and poses a risk to the entire laboratory. Additionally, cells should only be away from incubators for a minimal amount of time to preserve their integrity. These conditions call for multichannel pipettes (to expedite workflow) that are equipped with filter tips and fully autoclavable (to prevent contamination). (Learn more about the best practices for pipetting 3D cell culture hydrogels.)
  3. Microbiology - When studying bacteria, viruses, algae and other micro-organisms, contamination prevention is paramount. Mixing populations or introducing unwanted strains should be avoided. Best practices dictate aseptic working methods using sterilized lab equipment. Fully autoclavable pipettes with pre-sterilized tips and pipette controllers – fitted with sterile filters – are the optimal choice to achieve this ideal working environment.
  4. Chemicals - In chemical industry labs, it can be tricky to continuously achieve reliable results due to the aggressive nature of chemicals. Pipettes engineered for reliability (such as Proline® Plus) and paired with chemical-resistant pipette tips can make the job much easier. Chemical-resistant bottle top dispensers can also reduce spillage risks. (Explore on-demand webinar on best practices for pipetting in chemical labs.)

Ready for Action: Pipetting Techniques and Best Practices

You’ve found the perfect pipette for your workplace needs. You have accessorized your equipment with pipette tips, filters, stands and everything else you need to create a fully functional pipetting workspace. 

What now? 

Now is the time to make sure you are getting the most out of your pipette by going back to basics. By employing the best practices when using pipettes and pipetting equipment, not only is the life of the equipment prolonged, but sample/experiment integrity is preserved through elimination of error. 

Keep it Maintained: Pipette Maintenance Influences Equipment Performance

Service life cycle management is an important thing to consider when purchasing equipment. Whether the field is pharma, food and beverage, university, etc., good practices and preventative maintenance are crucial to increasing the longevity of equipment. And when the going gets tough, it also helps to know your lab equipment is backed by teams of exceptional repair and service professionals. To maintain the level of purity critical in many laboratory applications, adequate cleaning and decontamination of pipettes is necessary.

Within the confines of your testing parameters are a variety of factors which, over time, could affect the performance of your pipettes and pipetting accessories. No matter where you are in the world, we are prepared to serve you – and your pipette – with service contracts and a full spectrum of repair/maintenance options to suit your needs. Let us work with you to develop optimal service solutions for your systems, instruments, and pipetting equipment. With us on your support team, you can be sure of the quality of results through the final step of your manufacturing and testing processes. 

Keep it Calibrated: Pipette Calibration for Compliance and Efficiency

In addition to cleaning and performing routine maintenance on your pipettes, the accuracy and precision of these instruments should be checked at regular intervals (keeping in mind intervals can vary according to factors like frequency of use, pipetted materials, etc.).
 

With the right pipette calibration solutions, your laboratory can achieve: 

  1. Compliance – (Read Are You GLP/GMP Compliant When it Comes to Pipetting? )
  2. Decline in error frequency 
  3. Increased efficiency 
  4. Lower calibration costs 

Whether you prefer to outsource calibration services to our team of professionals or tackle the task in-house, we have everything needed to get the job done – and done well! 

Explore how to set up pipetting quality control program for your lab. Now you’re all set! We hope this one-stop guide puts you well on your way to pipette mastery, from equipment to technique to maintenance. We are confident our liquid-handling solutions will leave you wanting for nothing in your testing and manufacturing endeavors. Let us set you up for success in pharmaceutical discovery, bioengineering, quality control – whatever you might need. 

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